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AMYLOID A4 PROTEIN PRECURSOR
Descriptors Found:
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DeCS
Descriptor
English
:
Amyloid beta-Protein Precursor
Descriptor
Spanish
:
Precursor de Proteína beta-Amiloide
Descriptor
Portuguese
:
Precursor de Proteína beta-Amiloide
Synonyms
English
:
beta-Amyloid Protein Precursor
Amyloid Protein Precursor
Amyloid A4 Protein Precursor
Tree Number:
D12.776.049.407.249
D12.776.543.039
D12.776.645.468.500
D12.776.811.050
Definition
English
:
A single-pass type I membrane protein. It is cleaved by
AMYLOID PRECURSOR PROTEIN SECRETASES
to produce
peptides
of varying amino acid lengths. A 39-42 amino acid peptide,
AMYLOID BETA-PEPTIDES
is a principal component of the extracellular
amyloid
in SENILE PLAQUES.
History Note
English
:
92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30268
Unique Identifier:
D016564
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS